Welcome to BrainMix

Simple Culture for Advanced Brain Tissue Models

Revolutionising Neuroscience Research with an Easy, Cost-Effective, and Ethical Brain Model

Who we are

Advancing Neuroscience with Innovation and Impact

We are a team of neuroscientists from Keele University’s Neural Tissue Engineering Group, exploring the market potential of our frozen, mixed brain cell kit through the BBSRC-NC3Rs-ICURe programme.

Our goal is to provide a cost-effective, biologically relevant alternative to animal models and monocellular cultures, making complex brain research more accessible and scalable for academia, CROs, and the pharmaceutical industry.

Introducing BrainMix

The Challenge in Brain Research

Understanding and repairing the brain is a major challenge in research, largely due to its complex cellular interactions. However, researchers struggle to access brain models that are both user-friendly and biologically representative.

Current research options have significant limitations:

Animal Models

Expensive, technically demanding, and require specialist infrastructure, licensing, and ethical approval. Genetic models add further complexity, and excess animals from breeding programs often go to waste.

Immortalised Cell Lines

Lack multicellularity and often contain genetic abnormalities, making them unreliable for biological assays. Issues with contamination and unknown provenance further compromise research validity.

Primary Cells

Costly, time-intensive, and require technical expertise for isolation. Commercial options only offer single-cell types, failing to replicate the brain’s complex neuroarchitecture.

Our Solution

BrainMix is a ready-to-use frozen brain cell kit that enables researchers to easily establish complex, multicellular brain models in their own labs—without the need for specialist expertise or infrastructure. Simply thaw, revive and plate to start your cell culture experiments

One frozen vial (frozen for 7 days) can be thawed and plated resulting in a brain cell sheet consisting of multiple brain cell types

Why Choose BrainMix?

Brain-Mimetic

Contains all major brain cell types, including immune cells creating a realistic multicellular environment for more accurate data.

Easy & Quick

Takes just 1-2 hours to establish, compared to a full day of tissue derivation and culture setup.

Cost-Effective

Up to 5x cheaper than sourcing and combining individual cell types.

Reduces Animal Use

A viable alternative to live animal models, supporting ethical research.

Versatile

Future kits could be tailored for different brain regions, ages, and genetic models, expanding research possibilities.

Transforming Brain Research Across Sectors

BrainMix is designed to support cutting-edge research in academia, contract research organisations (CROs), and the pharmaceutical industry by providing a biologically relevant, scalable, and cost-effective alternative to traditional brain models.

Academic Research and Education

A ready-to-use, physiologically relevant brain model for advanced neuroscience research without extensive training and complex protocols. Beneficial for student projects through to large-scale research.

Contract Research Organisations (CROs)

A high-throughput, reproducible brain cell platform for efficient preclinical drug testing and toxicology studies.

Pharmaceutical & Biotech Companies

A scalable, cost-effective alternative to animal models for early-stage drug discovery and neurotherapeutic development.

Help Shape the Future of Brain Research

We are conducting a market exploration survey to better understand the needs of researchers like you. Your feedback will help us refine BrainMix and ensure it delivers maximum value.

The Experts Behind BrainMix

Dr Adams is a Senior Lecturer in Neuroscience (Keele University) who researches neural tissue engineering strategies to repair the damaged nervous system. He has considerable leadership experience as Program Director for the Neuroscience BSc and MRes in Bioscience courses at Keele and will lead the exploration journey.

Dr Chris Adams

Entrepreneurial Lead
Professor Divya Chari is Professor of Neural Tissue Engineering at the Keele University School of Medicine. Divya will provide expert scientific guidance to the team and has extensive experience in the project area. For example, her group has a track record of developing reductionist, 3D neural injury models to Reduce, Replace and Refine live animal experimentation, including leading work which underpins this project.

Professor Divya Maitreyi Chari

Principal Scientific Advisor
Tim is a business consultant who specializes in developing early-stage projects in the "valley of death," the challenging and high-risk funding gap between academia and industry. He has extensive experience in this field to draw on and guide the team in their market exploration journey.

Dr Tim Hammonds

Business Advisor
Dr Jacob Ranjbar is a biomedical scientist and entrepreneur with a PhD in Biomedical Engineering from Keele University (NC3Rs funded). He is MD of Science Engineered Limited, and will provide valuable advice and expertise in practical industrial solutions.

Dr Jacob Ranjbar

Commercial partner

Join Our Research Network

Interested in learning more about BrainMix, collaborating, or getting involved? We’d love to hear from you!